io9, a pretty cool new sci-fi blog, just posted "The Twenty Science Fiction Novels that Will Change Your Life".
The only one I have read:
I, Robot (1955), by Isaac AsimovUnless Will Smith is willing to make 19 more offensively unfaithful movie adaptations, I guess I have some reading to do.
This collection of linked short stories quite simply changed the way we think about robots. Asimov invented the "three laws of robotics," which are included in so many subsequent tales of humanoid robots and also in the work of robotics engineers. So this book has already changed your life, by changing robot history -- reading it, you'll be surprised how much this work of fiction has become accepted wisdom about the way real robots will function.
[The Twenty Science Fiction Novels that Will Change Your Life]